Amounts tested in patient studies
Tesamorelin doses and mixing steps used in trials.
This page reports what researchers gave and for how long. It does not tell you what dose to take.
What tesamorelin amounts the studies used
Drug makers created tesamorelin to restart natural growth hormone release. They compared several daily shot amounts in volunteers. For the main patient trials, 2 mg went beneath belly skin once a day [1][2]. Adults receiving HIV care lost organ fat at that amount.
A lower 1 mg shot appeared in diabetes and safety work [7]. The main fat-loss trials used the larger amount named above. Tesamorelin itself left blood within minutes. Its hormone response continued for twenty-four hours [10]. The studies therefore tested one shot per day.
These numbers describe the trials, not your dose. A doctor must weigh your health, other medicines, and the drug label. This page can't do that.
What each tesamorelin amount changed in blood tests
Most trial results come from one daily amount. Researchers injected tesamorelin 2 mg under the belly skin. Both large Phase 3 trials tested that 2 mg amount [1][2]. The liver-fat study used the same amount [6]. A lower 1 mg amount was used for comparison in a diabetes safety study [7].
An early trial asked whether different amounts changed the hormone response. Researchers enrolled 61 adults living with HIV. Patients received either 1 or 2 mg each day. IGF-1, a liver-made growth protein, rose in clear steps. It rose 48% with 1 mg. It rose 65% with 2 mg [8]. The 1 mg result is listed because the study compared two amounts. It isn't a second dose instruction. The higher amount caused the larger blood-test change. Researchers carried that amount into the final trials.
These are study amounts. They don't choose an amount for you.
Clinical access
Keep the prescribing decision separate from the study record
Clinical care at mypromise.com includes tesamorelin prescribing by Promise Peptides today, separate from these trial reports. A clinician licensed in the United States examines each individual request and may decide against a prescription. Patients must be in the United States, and the available choices change with the state and the treatment. A compounded tesamorelin medicine has no FDA approval.
How trial clinics mixed and stored tesamorelin
In the trials, tesamorelin came as sterile dry powder. It was packed in small glass vials. Nurses or patients added sterile water down the vial wall [5]. Hard shaking could damage the medicine. Staff slowly turned the vial until the liquid became clear.
The mixed medicine was used at once. Any liquid left in the vial was thrown away. Dry vials stayed cold and away from bright light. Each shot went just under the belly skin. Nurses changed the spot across the belly each day. That helped prevent sore or tender skin [4].
The shot went under skin, not into a vein or muscle.
Why one tesamorelin shot had effects all day
Tesamorelin left your blood fast, while the hormone response lasted longer. One study formula gave 1,060 liters per hour [10]. Your body doesn't contain that much fluid. The number is a math result that means quick removal. By day 14, blood tests found 13% more drug was taken up than on day 1 [10]. Your body was settling into a daily pattern. The change wasn't an unsafe buildup.
Half the drug was gone within thirty minutes. After 1 daily shot, little medicine remained in blood. Yet IGF-1 stayed raised for twenty-four hours. This growth protein comes from your liver. Its longer rise explains the study plan. Researchers chose one tesamorelin shot of 2 mg each day.
The schedule followed the hormone response. It didn't depend on tesamorelin staying in your blood.